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Completed Studies

YearsTitle 
2000-2008 Phase IV Registry of etanercept (Enbrel) in children with Juvenile Rheumatoid Arthritis. Data submitted for publication 
   
 2005-2008 A Pilot, Multi-Center, Randomized, Double Blind, Placebo Controlled, Ascending Dose, Safety, Tolerability and Preiminary Efficacy Study of Two Dose Levels of IL-1 Trap Administered Subcutaneously in Pediatric Subjects with Active Systemic Juvenile Idiopathic Arthritis (SJIA) 
   
2002-2004Clinical Protocol for a Randomized, Double-blind Multi-center, Active Controlled Parallel Group Study to Evaluate the Efficacy and Safety of Celecoxib Suspension Compared to Naproxen Suspension in Patients with JRA  
   
2002-2003Efficacy and Safety of Leflunomide versus Methorexate Comparison in Patients with Juvenile Rheumatoid Arthritis (JRA) 
   
2001-2003A Randomized, Double-blind Trial of Anti-TNF alpha Chimeric Monoclonal Antibody (INFLIXIMAB) in Combination with Methotrexate for the Treatment of Patients with Polyarticular JRA 
   
2001-A 52-Week, Open Label, Active Comparator Controlled Extension to a 12-Week Trial of Rofecoxib in Juvenile Rheumatoid Arthritis Patients 
   
2000-A 12-Week Double-Blind Randomized Trial, With a 12-Week Open Label Extension, to Investigate Efficacy and Safety of Meloxicam Oral Suspension Administered Once Daily and Naproxen Oral Suspension Administered Twice Daily in Children With JRA. 
   
2000-Safety and Efficacy of Meloxicam Oral Suspension in JRA (Subtrial of 107.208) 
   
2000-2003Development and Validation of Core Sets of Outcome Measures and Definitions of Improvement for Juvenile Dermatomyositis and Juvenile Systemic Lupus Erythematosus 
   
2000-2003A Randomized, Multi-center, Blinded, Placebo-controlled Study with an Open Label Run-in Period to Evaluate the Efficacy, Safety & Pharmacokinetics of Daily, Single, Subcutaneous Injections of r-metHUlL-Ira (Anakinra) in Polyarticular Course JRA 
   
2000-2003A Companion Extension Study to Evaluate the Long-term Safety of Daily, Single, Subcutaneous injections of r-metHulL-1ra (Anakinra) in Subjects with Polyarticular Course JRA who participated in IL-1ra (Protocol 990758) 
   
1999-An Open, Oral Dose Study to Evaluate the Steady State Plasma Concentration Profile of MK-0966, Followed by a 12-Week, Double-blind, Active-comparator-controlled Extension, in Late- and Post-pubertal Adolescents With Juvenile Rheumatoid Arthritis 
   
1999-2000Therapeutic Exploratory Trial of Cosamin DS in JRA 
   
1999-2002Neoral in Polyarticular Course JRA: Post-marketing Surveillance 
   
1998-2000Parenteral Methotrexate in Medium versus High-dosed for the Treatment of Idiopathic Arthritis of Childhood 
   
1998-1999Phase I Trial - Leflunomide in Poly course JRA 
   
1997-1998Safety, Population PK and Efficacy of Recombinant Human Tumor Necrosis Factor Receptor (P75) Fc Fusion Protein (TNFR:Fc) in Children with JRA 
   
1997-Open-label Treatment with TNFR:Fc in JRA 
   
1995-1996A Double-blind, Randomized, Vehicle-controlled, Parallel Group Multi-center Pilot Study Evaluating the Safety and Efficacy of Civamide Cream, 0.075% in Children with Pauciarticular Juvenile Rheumatoid Arthritis Disease of the Knee 
   
1994-1996Phase I/II study of DAB389IL-2 Fusion Toxin in Patients with Severe Polyarticular Juvenile Rheumatoid Arthritis 
   
1992-1996Intravenous Gammaglobulin (IVEEGAM) in Polyarticular Juvenile Rheumatoid Arthritis 
   
1990-1992   Intravenous Gammaglobulin in Severe Polyarticular JRA Patients  
 

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