Papers

    • Hermine Brunner, Nicolino Rupeto, Nikolay Tzaribachev, Gerd Horneff, Vyacheslav G. Chasnyk, Violeta Panaviene, Carlos Abud-Mendoza, Andreas Reiff, Ekaterina Alexeeva, Nadina Rubio-Pérez, Vladimir Keltsev, Daniel J Kingsbury, Maria del Rocio Maldonado Velázquez, Irina Nikishina, Earl D Silverman, Rik Joos, Elzbieta Smolewska, Márcia Bandeira, Kirsten Minden, Annet van Royen-Kerkhof, Wolfgang Emminger, Ivan Foeldvari, Bernard R Lauwerys, Flavio Sztajnbok, Keith E Gilmer, Zhenhua Xu, Jocelyn H Leu, Lilianne Kim, Sarah L Lamberth, Matthew J Loza, Daniel J Lovell, Alberto Martini,
      Subcutaneous Golimumab for Children with Active Polyarticular-Course Juvenile Idi-opathic Arthritis: Results of a Multicentre, Double-Blind, Randomised-Withdrawal Trial.
      Ann Rheum Dis, 2017 May 15, (), 2017. [ http ]

     

    • Arndt H. Brachat, Alexei A. Grom, Nico Wulffraat, Hermine I. Brunner, Pierre Quartier, Riva Brik, Liza McCann, Huri Ozdogan, Lidia Rutkowska-Sak Rayfel Schneider, Valeria Gerloni, Liora Harel, Maria Terreri, Kristin Houghton, Rik Joos, Daniel Kingsbury, Jorge M. Lopez-Benitez, Stephan Bek, Martin Schumacher, Marie-Anne Valentin, Hermann Gram, Ken Abrams, Alberto Martini, Daniel J. Lovell, Nanguneri R. Nirmala, Nicolino Ruperto and for the Pediatric Rheumatology International Trials Organization (PRINTO) the Pediatric Rheumatology Collaborative Study Group (PRCSG),
      Early changes in gene expression and inflammatory proteins in systemic juvenile idiopathic arthritis patients on canakinumab therapy.
      Arthritis Research & Therapy, 19-13 (), 2017. [ http ]

     

    • Angelo Ravelli, Francesca Minoia, Sergio Davì, AnnaCarin Horne, Francesca Bovis, Angela Pistorio, Maurizio Aricò, Tadej Avcin, Edward M. Behrens, Fabrizio De Benedetti, Lisa Filipovich, Alexei A. Grom, Jan-Inge Henter, Norman T. Ilowite, Michael B. Jordan, Raju Khubchandani, Toshiyuki Kitoh, Kai Lehmberg, Dan J. Lovell, Paivi Miettunen, Kim E. Nichols, Seza Ozen, Jana Pachlopnick-Schmid, Athimalaipet V. Ramanan, Ricardo Russo, Rayfel Schneider, Gary Sterba, Yosef Uziel, Carol Wallace, Carine Wouters, Nico Wulffraat, Erkan Demirkaya, Hermine I. Brunner, Alberto Martini, Nicolino Ruperto, Randy Q. Cron, on behalf of the Pediatric Rheumatology International Trials Organization, the Childhood Arthritis Rheumatology Research Alliance, the Pediatric Rheumatology Collaborative Study Group the Histiocyte Society,
      Development and initial validation of classification criteria for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.
      Arthritis & Rheumatology, 68 566-576 (3), 2016. [ http ]

     

    • Grom AA, Ilowite NT, Pascual V., Brunner H. I., Martini A., Lovell D., Ruperto N., Paediatric Rheumatology International Trials Organisation and the Pediatric Rheumatology Collaborative Study Group, Leon K, Lheritier K., Abrams K.,
      Rate and Clinical Presentation of Macrophage Activation Syndrome in Patients With Systemic Juvenile Idiopathic Arthritis Treated With Canakinumab..
      Arthritis & Rheumatology, 68 218-28 (1), 2016. [ http ]

     

    • Ravelli A, Minoia F, Davi S., Horne A., Bovis F., Pistorio A., Arico M., Avcin T. Behrens E. et al.,
      2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis..
      Ann Rheum Dis, 75 481-489, 2016. [ http ]

     

    • Fabrizio De Benedetti, Hermine Brunner, Nicolino Ruperto, Rayfel Schneider, Ricardo Xavier, Roger Allen, Diane E. Brown, Jeffrey Chaitow, Manuela Pardeo, Graciela Espada, Valeria Gerloni, Barry L. Myones, James W. Frane, Jianmei Wang, Terri H. Lipman, Kamal N. Bharucha, Alberto Martini, Daniel Lovell, for the Paediatric Rheumatology International Trials Organisation the Pediatric Rheumatology Collaborative Study Group,
      Catch-Up Growth During Tocilizumab Therapy for Systemic Juvenile Idiopathic Arthritis: Results From a Phase III Trial.
      Arthritis & Rheumatology, 67 840-848 (3), 2015. [ http ]

     

    • Daniel J. Lovell, Nicolino Ruperto, Richard Mouy, Eliana Paz, Nadina Rubio-Pérez, Clovis A. Silva, Carlos Abud-Mendoza, Ruben Burgos-Vargas, Valeria Gerloni, Jose A. Melo-Gomes, Claudia Saad-Magalhaes, J. Chavez-Corrales, Christian Huemer, Alan Kivitz, Francisco J. Blanco, Ivan Foeldvari, Michael Hofer, Hans-Iko Huppertz, Chantal Job Deslandre, Kirsten Minden, Marilynn Punaro, Alan J. Block, Edward H. Giannini, Alberto Martini, for the Pediatric Rheumatology Collaborative Study Group the Paediatric Rheumatology International Trials Organisation,
      Long-Term Safety, Efficacy, and Quality of Life in Patients With Juvenile Idiopathic Arthritis Treated With Intravenous Abatacept for Up to Seven Years.
      Arthritis & Rheumatology, 67 2759-2770 (10), 2015. [ http ]

     

    • Hermine I. Brunner, Nicolino Ruperto, Zbigniew Zuber, Caroline Keane, Olivier Harari, Andrew Kenwright, Peng Lu, Ruben Cuttica, Vladimir Keltsev, Ricardo M. Xavier, Inmaculada Calvo, Irina Nikishina, Nadina Rubio-Pérez, Ekaterina Alexeeva, Vyacheslav Chasnyk, Gerd Horneff, Violetta Opoka-Winiarska, Pierre Quartier, Clovis A. Silva, Earl Silverman, Alberto Spindler, Eileen Baildam, M. Luz Gámir, Alan Martin, Christoph Rietschel, Daniel Siri, Elzbieta Smolewska, Daniel Lovell, Alberto Martini, Fabrizio De Benedetti, for the Paediatric Rheumatology International Trials Organisation (PRINTO) the Pediatric Rheumatology Collaborative Study Group (PRCSG),
      Efficacy and safety of tocilizumab in patients with polyarticular-course juvenile idiopathic arthritis: results from a phase 3, randomised, double-blind withdrawal trial.
      Annals of the Rheumatic Diseases, 74 1110-1117 (6), 2015. [ http ]

     

    • Daniel J. Kingsbury, Brigitte Bader-Meunier, Gina Patel, Vipin Arora, Jasmina Kalabic Hartmut Kupper,
      Safety, effectiveness, and pharmacokinetics of adalimumab in children with polyarticular juvenile idiopathic arthritis aged 2 to 4 years.
      Clinical Rheumatology, 1-9, 2014. [ http ]

     

    • Rachel Sobel, Daniel Lovell, Hermine Brunner, Jennifer Weiss, Paula Morris, Beth Gottlieb, Elizabeth Chalom, Lawrence Jung, Karen Onel, Lisa Petiniot, Donald Goldsmith, Kabita Nanda, Michael Shishov, Staci Abramsky, James Young, Edward Giannini the Pediatric Rheumatology Collaborative Study Group,
      Safety of celecoxib and nonselective nonsteroidal anti-inflammatory drugs in juvenile idiopathic arthritis: results of the phase 4 registry.
      Pediatric Rheumatology, 12 29 (1), 2014. [ http ]

     

    • Michael Seid, Bin Huang, Stacey Niehaus, Hermine I. Brunner Daniel J. Lovell,
      Determinants of Health-Related Quality of Life in Children Newly Diagnosed With Juvenile Idiopathic Arthritis.
      Arthritis Care & Research, 66 263-269 (2), 2014. [ http ]

     

    • Sergio Davi, Francesca Minoia, Angela Pistorio, AnnaCarin Horne, Alessandro Consolaro, Silvia Rosina, Francesca Bovis, Rolando Cimaz, Maria Luz Gamir, Norman T. Ilowite, Isabelle Kone-Paut, Sheila Knupp Feitosa de Oliveira, Deborah McCurdy, Clovis Artur Silva, Flavio Sztajnbok, Elena Tsitsami, Erbil Unsal, Jennifer E. Weiss, Nico Wulffraat, Mario Abinun, Amita Aggarwal, Maria Teresa Apaz, Itziar Astigarraga, Fabrizia Corona, Ruben Cuttica, Gianfranco D'Angelo, Eli M. Eisenstein, Soad Hashad, Loredana Lepore, Velma Mulaosmanovic, Susan Nielsen, Sampath Prahalad, Donato Rigante, Valda Stanevicha, Gary Sterba, Gordana Susic, Syuji Takei, Ralf Trauzeddel, Mabruka Zletni, Nicolino Ruperto, Alberto Martini, Randy Q. Cron, Angelo Ravelli, the Childhood Arthritis on behalf of the Paediatric Rheumatology International Trials Organisation, Rheumatology Research Alliance, the Pediatric Rheumatology Collaborative Study Group the Histiocyte Society,
      Performance of Current Guidelines for Diagnosis of Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis.
      Arthritis & Rheumatology, 66 2871-2880 (10), 2014. [ http ]

     

    • Hermine I. Brunner, Nicolino Ruperto, Zbigniew Zuber, Caroline Keane, Olivier Harari, Andrew Kenwright, Peng Lu, Ruben Cuttica, Vladimir Keltsev, Ricardo M. Xavier, Inmaculada Calvo, Irina Nikishina, Nadina Rubio-Pérez, Ekaterina Alexeeva, Vyacheslav Chasnyk, Gerd Horneff, Violetta Opoka-Winiarska, Pierre Quartier, Clovis A. Silva, Earl Silverman, Alberto Spindler, Eileen Baildam, M. Luz Gámir, Alan Martin, Christoph Rietschel, Daniel Siri, Elzbieta Smolewska, Daniel Lovell, Alberto Martini, Fabrizio De Benedetti, for the Paediatric Rheumatology International Trials Organisation (PRINTO) the Pediatric Rheumatology Collaborative Study Group (PRCSG),
      Efficacy and safety of tocilizumab in patients with polyarticular-course juvenile idiopathic arthritis: results from a phase 3, randomised, double-blind withdrawal trial.
      Annals of the Rheumatic Diseases, 2014. [ http ]

     

    • Rina Mina, Marisa S. Klein-Gitelman, Shannen Nelson, B. Anne Eberhard, Gloria Higgins, Nora G. Singer, Karen Onel, Lori Tucker, Kathleen M. O'Neil, Marilynn Punaro, Deborah M. Levy, Kathleen Haines, Alberto Martini, Nicolino Ruperto, Daniel Lovell Hermine I. Brunner,
      Validation of the systemic lupus erythematosus responder index for use in juvenile-onset systemic lupus erythematosus.
      Annals of the Rheumatic Diseases, 73 401-406 (2), 2014. [ http ]

     

    • Carol A. Wallace, Edward H. Giannini, Steven J. Spalding, Philip J. Hashkes, Kathleen M. O'Neil, Andrew S. Zeft, Ilona S. Szer, Sarah Ringold, Hermine I. Brunner, Laura E. Schanberg, Robert P. Sundel, Diana Milojevic, Marilynn G. Punaro, Peter Chira, Beth S. Gottlieb, Gloria C. Higgins, Norman T. Ilowite, Yukiko Kimura, Stephanie Hamilton, Anne Johnson, Bin Huang, Daniel J. Lovell, for the Childhood Arthritis Rheumatology Research Alliance,
      Trial of early aggressive therapy in polyarticular juvenile idiopathic arthritis.
      Arthritis & Rheumatism, 64 2012-2021 (6), 2012. [ http ]

     

    • Fabrizio De Benedetti, Hermine I. Brunner, Nicolino Ruperto, Andrew Kenwright, Stephen Wright, Inmaculada Calvo, Ruben Cuttica, Angelo Ravelli, Rayfel Schneider, Patricia Woo, Carine Wouters, Ricardo Xavier, Lawrence Zemel, Eileen Baildam, Ruben Burgos-Vargas, Pavla Dolezalova, Stella M. Garay, Rosa Merino, Rik Joos, Alexei Grom, Nico Wulffraat, Zbigniew Zuber, Francesco Zulian, Daniel Lovell Alberto Martini,
      Randomized Trial of Tocilizumab in Systemic Juvenile Idiopathic Arthritis.
      New England Journal of Medicine, 367 2385-2395 (25), 2012. [ http ]

     

    • Nicolino Ruperto, Hermine I. Brunner, Pierre Quartier, Tamas Constantin, Nico Wulffraat, Gerd Horneff, Riva Brik, Liza McCann, Ozgur Kasapcopur, Lidia Rutkowska-Sak, Rayfel Schneider, Yackov Berkun, Inmaculada Calvo, Muferet Erguven, Laurence Goffin, Michael Hofer, Tilmann Kallinich, Sheila K. Oliveira, Yosef Uziel, Stefania Viola, Kiran Nistala, Carine Wouters, Rolando Cimaz, Manuel A. Ferrandiz, Berit Flato, Maria Luz Gamir, Isabelle Kone-Paut, Alexei Grom, Bo Magnusson, Seza Ozen, Flavio Sztajnbok, Karine Lheritier, Ken Abrams, Dennis Kim, Alberto Martini Daniel J. Lovell,
      Two Randomized Trials of Canakinumab in Systemic Juvenile Idiopathic Arthritis.
      New England Journal of Medicine, 367 2396-2406 (25), 2012. [ http ]

     

    • Daniel J. Lovell, Murray H. Passo, Timothy Beukelman, Suzanne L. Bowyer, Beth S. Gottlieb, Michael Henrickson, Norman T. Ilowite, Yukiko Kimura, Esi Morgan DeWitt, Jill Segerman, Leonard D. Stein, Janalee Taylor, Richard K. Vehe Edward H. Giannini,
      Measuring process of arthritis care: A proposed set of quality measures for the process of care in juvenile idiopathic arthritis.
      Arthritis Care & Research, 63 10-16 (1), 2011. [ http ]

     

    • Carol A. Wallace, Edward H. Giannini, Bin Huang, Lukasz Itert, Nicolino Ruperto, Childhood Arthritis Rheumatology Research Alliance (CARRA), Pediatric Rheumatology Collaborative Study Group (PRCSG) Paediatric Rheumatology International Trials Organisation (PRINTO),
      American College of Rheumatology provisional criteria for defining clinical inactive disease in select categories of juvenile idiopathic arthritis.
      Arthritis Care & Research, 63 929-936 (7), 2011. [ http ]

     

    • A. B. Gottlieb, K. Gordon, E. H. Giannini, P. Mease, J. Li, Y. Chon, J. Maddox, H. H. Weng, J. Wajdula, S. L. Lin S. W. Baumgartner,
      Clinical trial safety and mortality analyses in patients receiving etanercept across approved indications.
      J Drugs Dermatol, 10 289-300 (), 2011. [ ]

     

    • N. Ruperto, D. J. Lovell, P. Quartier, E. Paz N. Rubio-Perez,
      Long-Term Safety and Efficacy of Abatacept in Children with Juvenile Idiopathic Arthritis.
      Arthritis Rheum, (6) 1792-802 (), 2010. [ http ]

     

    • E. H. Giannini, N. T. Ilowite, D. J. Lovell, C. A. Wallace, et al for the Pediatric Rheumatology Collaborative Study Group,
      Effects of long-term etanercept treatment on growth in children with selected categories of juvenile idiopathic arthritis.
      Arthritis Rheum, Jul 28 (), 2010. [ http ]

     

    • N. Ruperto, E. H. Giannini, A. Pistorio, H. I. Brunner, A. Martini D. J. Lovell,
      Is it time to move to active comparator trials in juvenile idiopathic arthritis?.
      Arthritis Rheum, Jul 26 (), 2010. [ http ]

     

    • N. Ruperto, D. J. Lovell, T. Li, F. Sztajnbok, C. Goldenstein-Schainberg, et al the Pediatric Rheumatology Collaborative Study Group (PRCSG) , for the Paediaric Rheumatology International Trials Organization (PRINTO),
      Abatacept improves health-related quality of life, pain, sleep quality and daily participation in subjects with juvenile idiopathic arthritis.
      Arthritis Care Res, Jul 1 (), 2010. [ http ]

     

    • A. Martini D. J. Lovell,
      Juvenile idiopathic arthritis: state of the art and future perspectives.
      Ann Rheum Dis, (7) 1260-3 (), 2010. [ http ]

     

    • N. Ruperto, D. J. Lovell, R. Cuttica, P. Woo, S. Meiorin, et al , Paediatric Rheumatology International Trials Organization (PRINTO) Pediatric Rheumatology Collaborative Study Group (PRCSG),
      Long-term efficacy and safety of infliximab plus methotrexate for the treatment of polyarticular-course juvenile rheumatoid arthritis: findings from an open-label treatment extension.
      Ann Rheum Dis, 4 712-22 (), 2010. [ http ]

     

    • Nicolino Ruperto, Angela Pistorio, Angelo Ravelli, Lisa G. Rider, Clarissa Pilkington, Sheila Oliveira, Nico Wulffraat, Graciela Espada, Stella Garay, Ruben Cuttica, Michael Hofer, Pierre Quartier, Jose Melo-Gomes, Ann M. Reed, Malgorzata Wierzbowska, Brian M. Feldman, Miroslav Harjacek, Hans-Iko Huppertz, Susan Nielsen, Berit Flato, Pekka Lahdenne, Harmut Michels, Kevin J. Murray, Lynn Punaro, Robert Rennebohm, Ricardo Russo, Zsolt Balogh, Madeleine Rooney, Lauren M. Pachman, Carol Wallace, Philip Hashkes, Daniel J. Lovell, Edward H. Giannini, Boel Andersson Gare Alberto Martini,
      The Paediatric Rheumatology International Trials Organisation provisional criteria for the evaluation of response to therapy in juvenile dermatomyositis.
      Arthritis Care & Research, 62 1533-1541 (11), 2010. [ http ]

     

    • Nicolino Ruperto, Daniel J. Lovell, Tracy Li, Flavio Sztajnbok, Claudia Goldenstein-Schainberg, Morton Scheinberg, Inmaculada Calvo Penades, Michael Fischbach, Javier Orozco Alcala, Philip J. Hashkes, Christine Hom, Lawrence Jung, Loredana Lepore, Sheila Oliveira, Carol Wallace, Maria Alessio, Pierre Quartier, Elisabetta Cortis, Anne Eberhard, Gabriele Simonini, Irene Lemelle, Elizabeth Candell Chalom, Leonard H. Sigal, Alan Block, Allison Covucci, Marleen Nys, Alberto Martini Edward H. Giannini,
      Abatacept improves health-related quality of life, pain, sleep quality, and daily participation in subjects with juvenile idiopathic arthritis.
      Arthritis Care & Research, 62 1542-1551 (11), 2010. [ http ]

     

    • Edward H. Giannini, Norman T. Ilowite, Daniel J. Lovell, Carol A. Wallace, C. Egla Rabinovich, Andreas Reiff, Gloria Higgins, Beth Gottlieb, Pediatric Rheumatology Collaborative Study Group, Yun Chon, Nan Zhang Scott W. Baumgartner,
      Effects of long-term etanercept treatment on growth in children with selected categories of juvenile idiopathic arthritis.
      Arthritis & Rheumatism, 62 3259-3264 (11), 2010. [ http ]

     

    • Seza Ozen, Angela Pistorio, Silvia M. Iusan, Aysin Bakkaloglu, Troels Herlin, Riva Brik, Antonella Buoncompagni, Calin Lazar, Ilmay Bilge, Yosef Uziel, Donato Rigante, Luca Cantarini, Maria Odete Hilario, Clovis A. Silva, Mauricio Alegria, Ximena Norambuena, Alexandre Belot, Yackov Berkun, Amparo Ibanez Estrella, Alma Nunzia Olivieri, Maria Giannina Alpigiani, Ingrida Rumba, Flavio Sztajnbok, Lana Tambic-Bukovac, Luciana Breda, Sulaiman Al-Mayouf, Dimitrina Mihaylova, Vyacheslav Chasnyk, Claudia Sengler, Maria Klein-Gitelman, Djamal Djeddi, Laura Nuno, Chris Pruunsild, Jurgen Brunner, Anuela Kondi, Karaman Pagava, Silvia Pederzoli, Alberto Martini, Nicolino Ruperto for the Paediatric Rheumatology International Trials Organisation (PRINTO),
      EULAR/PRINTO/PRES criteria for Henoch-Schönlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part II: Final classification criteria.
      Annals of the Rheumatic Diseases, 69 798-806 (5), 2010. [ http ]

     

    • P. McCroskery, C. A. Wallace, D. J. Lovell, S. Stryker, N. Chernyukhin, C. Blosch D. J. Zack,
      Summary of worldwide pediatric malignancies reported after exposure to etanercept.
      Pediatr Rheumatol Online J, 8 18 (), 2010. [ ]

     

    • S. Visvanathan, C. Wagner, J. C. Marini, D. J. Lovell, A. Martini, R. Petty, R. Cuttica, P. Woo, G. Espada, M. Gattorno, M. T. Apaz, E. Baildam, A. Fasth, V. Gerloni, P. Lahdenne, P. Quartier, R. Saurenmann, S. Travers, A. Mendelsohn, S. Xu, E. H. Giannini N. Ruperto,
      The effect of infliximab plus methotrexate on the modulation of inflammatory disease markers in juvenile idiopathic arthritis: analyses from a randomized, placebo-controlled trial.
      Pediatr Rheumatol Online J, 8 24 (), 2010. [ ]

     

    • I. Foeldvari, I. S. Szer, L. S. Zemel, D. J. Lovell E. H. Giannini,
      A prospecitive study comparing celecoxib with naproxen in children with juvenile rheumatoid arthritis.
      J Rheumatol, 36 (1) 174-82 (), 2009. [ http ]

     

    • G. R. Burmester, P. J. Mease, B. A. Dinkmans, K. Gordon D. Lovell,
      Adalimumab safety and mortality rates from global clinical trials of six immune-mediated inflammatory diseases.
      Ann Rheum Dis, 1863-9 (), 2009. [ http ]

     

    • N. Ruperto, D. J. Lovell, R. Cuttica, P. Woo S. Meiorin,
      Long-Term Efficacy and Safety of Infliximab plus Methotrexate for The Treatment of Polyarticular Course Juvenile Rheumatoid Arthritis: Findings from an Open-Label Treatment Extension.
      Ann Rheum Dis, (), 2009. [ http ]

     

    • E. H. Giannini, N. T. Ilowite, D. J. Lovell, C. A. Wallace, C. E. Rabinovich et al ,
      Long-term safety and effectiveness of etanercept in children with selected categories of juvenile idiopathic arthritis.
      Arthritis Rheum, 60 2794-804 (9), 2009. [ http ]

     

    • N. Ruperto, A. Ravelli, A. Pistorio, V. Ferriani, I. Calvo, G. Ganser, J. Brunner, G. Dannecker, C. A. Silva, V. Stanevicha, R. T. Cate, L. W. van Suijlekom-Smit, O. Voygioyka, M. Fischbach, I. Foeldvari, O. Hilario, C. Modesto, R. K. Saurenmann, M. J. Sauvain, I. Scheibel, D. Sommelet, L. Tambic-Bukovac, R. Barcellona, R. Brik, S. Ehl, M. Jovanovic, J. Rovensky, F. Bagnasco, D. J. Lovell A. Martini,
      The provisional Paediatric Rheumatology International Trials Organisation/American College of Rheumatology/European League Against Rheumatism Disease activity core set for the evaluation of response to therapy in juvenile dermatomyositis: A prospective validation study..
      Arthritis Rheum, 59 (1) 4-13 (), 2008. [ ]

     

    • D. J. Lovell, N. Ruperto, S. Goodman, A. O. Reiff, L. Jung, K. Jarosova, D. Nemcova, R. Mouy, C. Sandborg, J. Bohnsack, D. Elewaut, I. Foeldvari, V. Gerloni, J. Rovensky, K. Minden, R. Vehe, L. Wagner-Weiner, G. Horneff, H. I. Huppertz, N. Y. Olson, J. R. Medich, R. Carcereri-De-Prati, M. J. McIlraith, E. H. Giannini A. Martini,
      A randomized, placebo-controlled trial of adalimumab with or without methotrexate in children with polyarticular juvenile rheumatoid arthritis.
      N Engl J Med, Vol. 359 810-820 (No. 8), 2008. [ http ]

     

    • et al Lovell, DJ, A. O. Reiff, N. T. Ilowite, C. A. Wallace, Y. Chon, S. L. Lin, S. W. Baumgartner E. H. Giannini,
      Safety and Efficacy of up to 8 years of continuous etanercept therapy in patients with juvenile rheumatoid arthritis.
      Arthritis Rheum, 58 1496-504 ((5)), 2008. [ http ]

     

    • N. Ruperto, D. J. Lovell, E. H. Giannini A. Martini,
      Efficacy and safety of abatacept in children with juvenile idiopathic arthritis: A randomized, double-blink, placebo controlled withdrawal trial.
      Lancet, 372 383-391 (), 2008. [ http ]

     

    • N. Ruperto, D. J. Lovell E. H. Giannini,
      Abatacept in children with juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled withdrawal trial.
      Lancet, 372 (9636) 383-391 (), 2008. [ http ]

     

    • D. J. Lovell, N. Ruperto, S. Goodman A. Reiff,
      Adalimumab with or without methotrexate in juvenile rheumatoid arthritis.
      N Engl J Med, 359 (8) 810-820 (), 2008. [ http ]

     

    • N. Ruperto, D. J. Lovell, R. Cuttica, N. Wilkinson, P. Woo, G. Espada, C. Wouters, E. D. Silverman, Z. Balogh, M. Henrickson, M. T. Apaz, E. Baildam, A. Fasth, V. Gerloni, P. Lahdenne, A. M. Prieur, A. Ravelli, R. K. Saurenmann, M. L. Gamir, N. Wulffraat, L. Marodi, R. E. Petty, R. Joos, F. Zulian, D. McCurdy, B. L. Myones, K. Nagy, P. Reuman, I. Szer, S. Travers, A. Beutler, G. Keenan, J. Clark, S. Visvanathan, A. Fasanmade, A. Raychaudhuri, A. Mendelsohn, A. Martini E. H. Giannini,
      A randomized, placebo-controlled trial of infliximab plus methotrexate for the treatment of polyarticular-course juvenile rheumatoid arthritis.
      Arthritis Rheum, 56 3096-3106 (), 2007. [ ]

     

    • D. J. Lovell, A. Reiff O. Y. Jones,
      Long-term safety and efficacy of etanercept in children with polyarticular-course juvenile rheumatoid arthritis.
      Arthritis & Rheumatism, 54 1987-1994 (), 2006. [ http ]

     

    • N. Ruperto, A. Ravelli, E. Castell, V. Gerloni, R. Haefner, C. Malattia, F. Kanakoudi-Tsakalidou, S. Nielsen, J. Bohnsack, D. Gibbas, R. Rennebohm, O. Voygioyka, Z. Balogh, L. Lepore, E. Macejkova, N. Wulffraat, S. Oliveira, R. Russo, A. Buoncompagni, M. O. Hilario, M. G. Alpigiani, M. Passo, D. J. Lovell, R. Merino, A. Martini E. H. Giannini,
      Cyclosporine A in juvenile idiopathic arthritis. Results of the PRCSG/PRINTO phase IV post marketing surveillance study..
      Clin Exp Rheumatol, 24 599-605 (5), 2006. [ http ]

     

    • A. Reiff, D. J. Lovell, J. Van Adelsberg, M. H. B. Kiss, S. Goodman, M. F. Zavaler, P. Y. Chen, J. A. Bolognese, P. Cavanaugh Jr, A. S. Reicin E. H. Giannini,
      Evaluation of the comparative efficacy and tolerability of rofecoxib and naproxen in children and adolescents with juvenile rheumatoid arthritis: a 12-week randomized controlled clinical trial with a 52-week open-label extension..
      J Rheumatol, 33 985-995 (5), 2006. [ http ]

     

    • C. A. Wallace, N. Ruperto E. H. Giannini,
      Preliminary criteria for clinical remission for selected categories of juvenile idiopathic arthritis.
      J Rheumatol, 31 2290-2294 (), 2004. [ http ]

     

    • L. G. Rider, E. H. Giannini, H. I. Brunner, N. Ruperto, L. James-Newton, A. M. Reed, P. A. Lachenbruch F. W. Miller,
      International consensus on preliminary definitions of improvement in adult and juvenile myositis..
      Arthritis Rheum, 50 2281-90 (7), 2004. [ http ]

     

    • L. G. Rider, E. H. Giannini, M. Harris-Love, G. Joe, D. Isenberg, C. Pilkington, P. A. Lachenbruch F. W. Miller,
      Defining Clinical Improvement in Adult and Juvenile Myositis.
      J Rheumatol, 30 603-617 ((3)), 2003. [ http ]

     

    • D. J. Lovell, E. H. Giannini, A. Reiff, O. Y. Jones, R. Schneider, J. C. Olson, L. D. Stein, A. Gedalia, N. T. Ilowite, C. A. Wallace, Mary Lange, B. K. Finck D. J. Burge,
      Long-term efficacy and safety of etanercept in children with polyarticular-course juvenile rheumatoid arthritis: interim results from an ongoing multicenter, open-label, extended-treatment trial..
      Arthritis Rheum, 48 218-26 (1), 2003. [ http ]

     

    • N. Ruperto, A. Ravelli, K. J. Murray, D. J. Lovell, B. Andersson-Gare, B. M. Feldman, S. Garay, W. Kuis, C. Machado, L. Pachman, A. M. Prieur, L. G. Rider, E. Silverman, E. Tsitsami, P. Woo, E. H. Giannini A. Martini,
      Preliminary core sets of measures for disease activity and damage assessment in juvenile systemic lupus erythematosus and juvenile dermatomyositis..
      Rheumatology (Oxford), 42 1452-9 (12), 2003. [ http ]

     

    • H. I. Brunner, D. J. Lovell, B. K. Finck E. H. Giannini,
      Preliminary definitions of disease flare in juvenile rheumatoid arthritis (JRA)..
      J Rheumatol, 29 1058-64 (), 2002. [ ]

     

    • D. J. Lovell, E. H. Giannini, A. Reiff, G. D. Cawkwell, E. D. Silverman, J. J. Nocton, L. D. Stein, A. Gedalia, N. T. Ilowite, C. A. Wallace, J. Whitmore B. K. Finck,
      Etanercept in children with polyarticular juvenile rheumatoid arthritis. Pediatric Rheumatology Collaborative Study Group..
      N Engl J Med, 342 763-9 (11), 2000. [ http ]

     

    • D. J. Lovell, C. B. Lindsley, R. M. Rennebohm, S. H. Ballinger, S. L. Bowyer, E. H. Giannini, J. E. Hicks, J. E. Levinson, R. Mier, L. M. Pachman, M. H. Passo, M. D. Perez, A. M. Reed, K. N. Schikler, M. Smith, L. S. Zemel L. G. Rider,
      Development of validated disease activity and damage indices for the juvenile idiopathic inflammatory myopathies. II. The Childhood Myositis Assessment Scale (CMAS): a quantitative tool for the evaluation of muscle function. The Juvenile Dermatomyositis Disease Activity Collaborative Study Group..
      Arthritis Rheum, 42 2213-9 (10), 1999. [ http ]

     

    • N. Ruperto, J. E. Levinson, A. Ravelli, E. S. Shear, B. L. Tague, K. Murray, A. Martini E. H. Giannini,
      Long-term health outcomes and quality of life in American and Italian inception cohorts of patients with juvenile rheumatoid arthritis. I. Outcome status.
      J Rheumatol, 24 945-951 (), 1997. [ http ]

     

    • N. Ruperto, A. Ravelli, J. E. Levinson, E. S. Shear, K. Murray, B. L. Tague, A. Martini, D. N. Glass E. H. Giannini,
      Long-term health outcomes and quality of life in American and Italian inception cohorts of patients with juvenile rheumatoid arthritis. II. Early predictors of outcome..
      J Rheumatol, 24 952-958 (), 1997. [ http ]

     

    • E. H. Giannini, N. Ruperto, A. Ravelli, D. J. Lovell, D. T. Felson A. Martini,
      Preliminary definition of improvement in juvenile arthritis..
      Arthritis Rheum, 40 1202-9 (7), 1997. [ http ]

     

    • N. Ruperto E. H. Giannini,
      Redundancy of conventional articular response variables used in juvenile chronic arthritis clinical trials..
      Ann Rheum Dis, 55 73-5 (1), 1996. [ http ]

     

    • E. H. Giannini, D. J. Lovell, E. D. Silverman, R. P. Sundel, B. L. Tague N. Ruperto,
      Intravenous immunoglobulin in the treatment of polyarticular juvenile rheumatoid arthritis: a phase I/II study. Pediatric Rheumatology Collaborative Study Group..
      J Rheumatol, 23 919-24 (5), 1996. [ http ]

     

    • E. H. Giannini, D. J. Lovell B. Hepburn,
      FDA draft guidelines for the clinical evaluation of anti-inflammatory and anti-rheumatic drugs in children. Executive summary..
      Arthritis Rheum, 38 715-8 (5), 1995. [ http ]

     

    • E. D. Silverman, G. D. Cawkwell, D. J. Lovell, R. M. Laxer, T. J. Lehman, M. H. Passo, L. S. Zemel E. H. Giannini,
      Intravenous immunoglobulin in the treatment of systemic juvenile rheumatoid arthritis: a randomized placebo controlled trial. Pediatric Rheumatology Collaborative Study Group..
      J Rheumatol, 21 2353-8 (12), 1994. [ http ]

     

    • E. H. Giannini, J. T. Cassidy, E. J. Brewer, A. Shaikov, A. Maximov N. Kuzmina,
      Comparative efficacy and safety of advanced drug therapy in children with juvenile rheumatoid arthritis..
      Semin Arthritis Rheum, 23 34-46 (1), 1993. [ http ]

     

    • E. H. Giannini, E. J. Brewer, N. Kuzmina, A. Shaikov, A. Maximov, I. Vorontsov, C. W. Fink, A. J. Newman, J. T. Cassidy L. S. Zemel,
      Methotrexate in resistant juvenile rheumatoid arthritis. Results of the U.S.A.-U.S.S.R. double-blind, placebo-controlled trial. The Pediatric Rheumatology Collaborative Study Group and The Cooperative Children's Study Group..
      N Engl J Med, 326 1043-9 (16), 1992. [ http ]

     

    • E. H. Giannini, K. S. Barron, C. H. Spencer, D. A. Person, J. Baum, B. H. Bernstein, D. W. Kredich, J. C. Jacobs, L. S. Zemel D. Gibbas,
      Auranofin therapy for juvenile rheumatoid arthritis: results of the five-year open label extension trial..
      J Rheumatol, 18 1240-2 (8), 1991. [ http ]

     

    • E. H. Giannini, E. J. Jr Brewer, N. Kuzmina, A. Shaikov B. Wallin,
      Auranofin in the treatment of juvenile rheumatoid arthritis. Results of the USA-USSR double-blind, placebo-controlled trial. The USA Pediatric Rheumatology Collaborative Study Group. The USSR Cooperative Children's Study Group..
      Arthritis Rheum, 33 466-76 (4), 1990. [ http ]

     

    • E. H. Giannini, E. J. Brewer, M. L. Miller, D. Gibbas, M. H. Passo, H. M. Hoyeraal, B. Bernstein, D. A. Person, C. W. Fink L. A. Sawyer,
      Ibuprofen suspension in the treatment of juvenile rheumatoid arthritis. Pediatric Rheumatology Collaborative Study Group..
      J Pediatr, 117 645-52 (4), 1990. [ http ]

     

    • K. A. Sheerin, E. H. Giannini, E. J. Jr Brewer K. S. Barron,
      HLA-B27-associated arthropathy in childhood: Long-term clinical and diagnostic outcome..
      Arthritis Rheum, 31 1165-70 (9), 1988. [ http ]

     

    • C. van Kerckhove, E. H. Giannini D. J. Lovell,
      Temporal patterns of response to D-penicillamine, hydroxychloroquine, and placebo in juvenile rheumatoid arthritis patients..
      Arthritis Rheum, 31 1252-8 (10), 1988. [ http ]

     

    • E. H. Giannini, E. J. Brewer, N. Kuzmina, L. Alekseev B. P. Shokh,
      Characteristics of responders and nonresponders to slow-acting anti-rheumatic drugs (SAARDs) in juvenile rheumatoid arthritis..
      Arthritis Rheum, 31 15-20 (1), 1988. [ http ]

     

    • I. L. Arroyo, E. J. Brewer E. H. Giannini,
      Arthritis/arthralgia and hypermobility of the joints in schoolchildren..
      J Rheumatol, 15 978-80 (6), 1988. [ http ]

     

    • E. H. Giannini E. J. Brewer,
      Poor correlation between the erythrocyte sedimentation rate and clinical activity in juvenile rheumatoid arthritis..
      Clin Rheumatol, 6 197-201 (2), 1987. [ http ]

     

    • E. H. Giannini, E. J. Brewer, D. A. Person X. He,
      Long-term auranofin therapy in patients with juvenile rheumatoid arthritis.
      J Rheumatol, 314 1269-1276 (), 1986. [ http ]

     

    • E. J. Brewer, E. H. Giannini, N. Kuzmina L. Alekseev,
      Penicillamine and hydroxychloroquine in the treatment of severe juvenile rheumatoid arthritis. Results of the U.S.A.-U.S.S.R. double-blind placebo-controlled trial..
      N Engl J Med, 314 1269-76 (20), 1986. [ http ]

     

    • A. Gedalia, D. A. Person, E. J. Jr Brewer E. H. Giannini,
      Hypermobility of the joints in juvenile episodic arthritis/arthralgia..
      J Pediatr, 107 873-6 (6), 1985. [ http ]

     

    • J. C. Bass, B. H. Athreya, E. J. Brewer, E. H. Giannini, D. P. Goldsmith, J. R. Hollister, D. W. Kredich, N. E. Brandstrup, J. J. Miller L. M. Pachman,
      A once-daily anti-inflammatory drug, oxaprozin, in the treatment of juvenile rheumatoid arthritis. The Pediatric Rheumatology Collaborative Study Group..
      J Rheumatol, 12 384-6 (2), 1985. [ http ]

     

    • E. H. Giannini, E. J. Brewer D. A. Person,
      Blood gold concentrations in children with juvenile rheumatoid arthritis undergoing long-term oral gold therapy..
      Ann Rheum Dis, 43 228-31 (2), 1984. [ http ]

     

    • D. J. Lovell, E. H. Giannini E. J. Jr Brewer,
      Time course of response to non-steroidal anti-inflammatory drugs in juvenile rheumatoid arthritis..
      Arthritis Rheum, 27 1433-7 (12), 1984. [ http ]

     

    • E. J. Jr Brewer, E. H. Giannini D. A. Person,
      Early experiences with auranofin in juvenile rheumatoid arthritis..
      Am J Med, 75 152-6 (6A), 1983. [ http ]

     

    • E. H. Giannini, E. J. Jr Brewer D. A. Person,
      Auranofin in the treatment of juvenile rheumatoid arthritis..
      J Pediatr, 102 138-41 (1), 1983. [ http ]

     

    • E. H. Giannini, D. A. Person, E. J. Brewer D. B. Parks,
      Blood and serum concentrations of gold after a single dose of auranofin in children with juvenile rheumatoid arthritis..
      J Rheumatol, 10 496-8 (3), 1983. [ http ]

     

    • E. J. Brewer, E. H. Giannini, J. Baum, J. T. Cassidy, C. W. Fink, V. Hanson, J. C. Jacobs J. G. Schaller,
      Sodium meclofenamate (Meclomen) in the treatment of juvenile rheumatoid arthritis. A segment I study..
      J Rheumatol, 9 129-134 (), 1982. [ http ]

     

    • E. J. Brewer, E. H. Giannini, J. Baum, C. W. Fink, V. Hanson, J. C. Jacobs J. G. Schaller,
      Proquazone (Biarsan) in the treatment of juvenile rheumatoid arthritis. A segment I study..
      J Rheumatol, 9 135-139 (), 1982. [ http ]

     

    • J. C. Bass, E. H. Giannini, E. J. Brewer, B. H. Athreya, N. E. Brandstrup, D. P. Goldsmith, J. J. Miller L. M. Pachman,
      Pirprofen (Rengasil) in the treatment of juvenile rheumatoid arthritis. A segment I study..
      J Rheumatol, 9 140-3 (1), 1982. [ http ]

     

    • E. J. Brewer E. H. Giannini,
      Standard methodology for Segment I, II, and III Pediatric Rheumatology Collaborative Study Group studies. I. Design..
      J Rheumatol, 9 109-13 (1), 1982. [ http ]

     

    • E. H. Giannini E. J. Brewer,
      Standard methodology for Segment I, II, and III Pediatric Rheumatology Collaborative Study Group studies. II. Analysis and presentation of data.
      J Rheumatol, 9 114-122 (1), 1982. [ http ]

     

    • E. J. Brewer, E. H. Giannini, J. Baum, B. Bernstein, C. W. Fink, H. M. Emery J. G. Schaller,
      Aspirin and fenoprofen (Nalfon) in the treatment of juvenile rheumatoid arthritis results of the double blind-trial. A segment II study.
      J Rheumatol, 9 123-128 (1), 1982. [ http ]

     

    • E. J. Brewer, E. H. Giannini, J. Baum, B. Bernstein, C. W. Fink, J. G. Schaller C. M. Knee,
      Ketoprofen (Orudis) in the treatment of juvenile rheumatoid arthritis. A segment I study.
      J Rheumatol, 9 144-148 (1), 1982. [ http ]

     

    • E. J. Brewer, R. W. Nickeson, R. D. Rossen, D. A. Person, E. H. Giannini J. D. Milam,
      Plasma exchange in selected patients with juvenile rheumatoid arthritis..
      J Pediatr, 98 194-200 (), 1981. [ http ]

     

    • E. J. Brewer, E. H. Giannini E. Barkley,
      Gold Therapy in the Management of Juvenile Rheumatoid Arthritis.
      Arthritis Rheum, 23 404-411 (), 1980. [ http ]

     

    • E. J. Brewer, E. H. Giannini, R. D. Rossen, B. Patten E. Barkley,
      Plasma exchange therapy of a childhood onset dermatomyositis patient..
      Arthritis Rheum, 23 509-513 (), 1980. [ http ]

     

    • J. E. Levinson, J. Baum, E. Brewer, Jr, C. Fink, V. Hanson J. Schaller,
      Comparison of tometin sodium and aspirin in the treatment of juvenile rheumatoid arthritis.
      J Pediatr, 91 799-804 (5), 1977. [ http ]